RBM 20 orchestrates pre - mRNA processing by targeting distinct intronic splicing silencers in the heart

نویسندگان

  • Henrike Maatz
  • Marvin Jens
  • Martin Liss
  • Sebastian Schafer
  • Matthias Heinig
  • Marieluise Kirchner
  • Eleonora Adami
  • Carola Rintisch
  • Vita Dauksaite
  • Michael H Radke
  • Matthias Selbach
  • Paul JR Barton
  • Stuart A Cook
  • Nikolaus Rajewsky
  • Michael Gotthardt
  • Markus Landthaler
  • Norbert Hubner
چکیده

1 Max-Delbrück-Center for Molecular Medicine (MDC), 13125 Berlin, Germany; 2 Systems Biology of Gene Regulatory Elements, Max-Delbrück-Center for Molecular Medicine, 13125 Berlin, Germany, 3 Neuromuscular and Cardiovascular Cell Biology, Max-Delbrück-Center for Molecular Medicine, 13125 Berlin, Germany; 4 Department of Computational Biology, Max Planck Institute for Molecular Genetics, 14195 Berlin, Germany; 5 Laboratory of Cell Signaling and Mass Spectrometry, Max Delbrück Center for Molecular Medicine, 13125 Berlin, Germany; 6 National Heart and Lung Institute, Cardiovascular Genetics and Genomics, Sydney Street, London SW3 6NP, UK; 7 Royal Brompton NIHR Cardiovascular Biomedical Research Unit, London, SW3 6NP, UK; 8 Duke-NUS Graduate Mediacl School, 8 College Road, Singapore 169857; 9 National Heart Center Singapore, 5 Hospital Drive Singapore, 169609; 10 DZHK (German Centre for Cardiovascular Research), partner site Berlin, Berlin, Germany; 11 RNA Biology and Posttranscriptional Regulation, Max-Delbrück-Center for Molecular Medicine, 13125 Berlin, Germany; 12 These authors contributed equally to this work

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تاریخ انتشار 2014